Latest results from the lab
The Intra-membrane Assembly of the Fas receptor Revealed
Fas/CD95 is an apoptosis-inducing death receptor. Fu et al. determined the transmembrane domain structure of Fas and showed that the trimer assembly, which is mediated by a proline-containing motif, is essential for Fas signaling. The study is published in Fu et al, Molecular Cell. 2016, 61(4):602-13.
NMR Structure of the Bacterial Electron Transporter
The first view of a transmembrane electron transporter has finally been obtained. The NMR structure of the CcdA transmembrane reductase in the reduced state is published in Williamson & Cho et al, Nat Struct Mol Biol. 2015, Oct;22(10):809-14.
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