^ - equal contribution authors     * - co-corresponding authors
  1. Wang J, Pielak RM, McClintock MA, Chou JJ: Solution structure and functional analysis of the influenza B proton channel. Nature Struct Mol Biol, Nov, (2009).

  2. Pielak RM^, Schnell JR^*, Chou JJ*: Mechanism of drug inhibition and drug resistance of influenza A M2 channel. Proc Natl Acad Sci, 106(18):7379-84 (2009). PDF, Supp Info

  3. Yoon MK^, Venkatachalam V^, Huang A, Choi BS*, Stultz CM*, Chou JJ*: Residual structure within the disordered C-terminal segment of p21Waf1/Cip1/Sdi1 and its implications for molecular recognition. Protein Science, 18(2), 337-347 (2008).

  4. Xu C^, Gagnon E^, Call ME, Schnell JR, Schwieters CD, Carman CV, Chou JJ*, Wucherpfennig KW*: Regulation of T Cell Receptor Activation by Dynamic Membrane Binidng of the CD3e Cytoplasmic Tyrosine-Based Motif. Cell, 135(4), 702-713 (2008). PDF

  5. Sharma AK, Zhou GP, Kupferman J, Surks HK, Christensen EN, Chou JJ, Mendelsohn ME, Rigby AC: Probing the interaction between the coiled coil leucine zipper of cGMP-dependent protein kinase Ialpha and the C terminus of the myosin binding subunit of the myosin light chain phosphatase. J Biol Chem, 283(47):32860-9 (2008).

  6. Shen H, Chou JJ: MemBrain: Improving the Accuracy of Predicting Transmembrane Helices. PLoS ONE, 3(6), e2399 (2008). PDF Available

  7. Schnell JR, Chou JJ: Structure and mechanism of the M2 proton channel of influenza A virus. Nature, 451(7178), 591-5 (2008). PDF Available

  8. Oxenoid K, Rice AJ, Chou JJ: Comparing the structure and dynamics of phospholamban pentamer in its unphosphorylated and pseudo-phosphorylated states. Protein Science, 16(9), 1977-83 (2007). PDF Available

  9. Douglas SM, Chou JJ*, Shih WM*: DNA-nanotube-induced alignment of membrane proteins for NMR structure determination. Proc. Natl. Acad. Sci, 104(16), 6644-6648 (2007). PDF Available

  10. Mansy SS, Zhang J, Kummerle R, Nilsson M, Chou JJ, Szostak JW, Chaput JC: Structure and evolutionary analysis of a non-biological ATP-binding protein. J Mol Biol, 371, 501-13 (2007).

  11. Kubat JA, Chou JJ, Rovnyak D: Nonuniform sampling and maximum entropy reconstruction applied to the accurate measurement of residual dipolar couplings. J Magn Reson, 186, 201-11, (2007).

  12. Call ME^, Schnell JR^, Xu C, Lutz RA, Chou JJ*, Wucherpfennig KW*: The Structure of the ζζ Transmembrane Dimer Reveals Features Essential for Its Assembly with the T Cell Receptor. Cell, 127(2), 355-368 (2006). PDF Available

  13. Potluri S, Yan AK, Chou JJ, Donald BR, Bailey-Kellogg C: Structure Determination of Symmetric Homo-Oligomers by a Complete Search of Symmetry Configuration Space, Using NMR Restraints and van der Waals Packing. PROTEINS: Structure, Function, and Bioinformatics, 65, 203-219 (2006). PDF Available

  14. Wei RR, Schnell JR, Larsen NA, Sorger PK, Chou JJ, Harrison SC: Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain. Structure, 14(6), 1003-9 (2006). PDF Available

  15. Carothers JM, Davis JH, Chou JJ, Szostak JW: Solution structure of an informationally complex high-affinity RNA aptamer to GTP. RNA, 12, 567-79 (2006).

  16. Zweckstetter M, Schnell JR, Chou JJ: Determination of the Packing Mode of the Coiled-coil Domain of cGMP-dependent Protein Kinase Ia in Solution Using Charge-Predicted Dipolar Couplings. J. Am. Chem. Soc., 127, 11918-9 (2005). PDF Available

  17. Schnell, J. R., Zhou, G., Zweckstetter, M., Rigby, A. C., Chou, J. J.: Rapid and Accurate Structure Determination of Coiled-coil Domains Using NMR Dipolar Couplings: Application to cGMP-dependent Protein Kinase Ia. Protein Science, 14(9), 2421-8 (2005). PDF Available

  18. Oxenoid K, Chou JJ: The structure of phospholamban pentamer reveals a channel-like architecture in membranes. Proc. Natl. Acad. Sci., 102, 10870-10875 (2005). PDF Available

  19. Zhou X, Chou JJ*, Wong ST*: Protein Structure Similarity Analysis by Using Interaction Matrix Based Principle Component Correlation. BMC Bioinformatics., 7:40 (2006). PDF Available

  20. Wang JF, Schnell JR, Chou JJ: Amantadine partition and localization in phospholipids membrane: a solution NMR study. Biochem. Biophys. Research Comm., 324, 212-217 (2004). PDF Available

  21. Chou JJ, Baber JL, Bax A: Characterization of phospholipids mixed micelles by translational diffusion. J. Biol. NMR, 29, 299-308 (2004). PDF Available

  22. Chou JJ, Case D, Bax A: Insights in mobility of methyl-bearing sidechains in proteins from Jcc and Jcn couplings. J. Am. Chem. Soc., 125, 8959-8966 (2003). PDF Available

  23. Chou JJ, Kaufman JD, Stahl SJ, Wingfield PT, Bax A: Micelle-Induced Curvature in a Water-Insoluble HIV-1 Env Peptide Revealed by NMR Dipolar Coupling Measurement in Stretched Polyacrylamide Gel. J. Am. Chem. Soc., 124, 2450-2451 (2002). PDF Available

  24. Chou JJ, Li S, Klee CB, Bax A: Solution structure of Ca2+–calmodulin reveals flexible hand-like properties of its domains.  Nature Structural Biology, 8, 990-997 (2001). PDF Available

  25. Chou JJ, Bax A: Protein Side-Chain Rotamers from Dipolar Couplings in a Liquid Crystalline Phase. J. Am. Chem. Soc., 123, 3844-3845 (2001).

  26. Bax A, Chou JJ, Ramirez B: Invited Review:  Liquid Crystalline Samples: Application to Macromolecular Structure Determination. Methods in Enzymology (2001).

  27. Chou JJ^, Gaemers S^, Howder B, Louis JM, Bax A: A simple apparatus for generating stretched polyacrylamide gels, yielding uniform alignment of proteins and detergent micelles. J. Biol. NMR, 21, 377-382 (2001).

  28. Chou JJ, Li S, Bax A: Study of Conformational Rearrangement and Refinement of Structural Homology Models by the Use of Heteronuclear Dipolar Couplings. J. Biol. NMR, 18, 217-227 (2000).

  29. Chou JJ, Delaglio F, Bax A: Measurement of One-Bond 15N-13C’ Dipolar Couplings in Medium Sized Proteins. J. Biol. NMR, 18, 101-105 (2000).

  30. Chou JJ, Li H, Salvessen GS, Yuan J, Wagner G: Solution Structure of BID, an Intracellular Amplifier of Apoptotic Signaling. Cell, 96, 615-624 (1999).

  31. Zhou P, Chou JJ, Olea RS, Yuan J, Wagner G: Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: A structural basis for specific adaptor/caspase interaction, Proc. Natl. Acad. Sci., 96, 11265-11270 (1999)

  32. Lugovskoy AA, Zhou P, Chou JJ, McCarty JS, Li P, Wagner G: Solution Structure of the CIDE-N Domain of CIDE-B and a Model for CIDE-N/CIDE-N Interactions in the DNA Fragmentation Pathway of Apoptosis. Cell, 99, 747–755 (1999).

  33. Chou JJ, Matsuo H, Duan H, Wagner G: Solution Structure of the RAIDD CARD Domain and Model for CARD/CARD Interaction in Caspase-2 and Caspase-9 Recruitment. Cell, 94, 171-180 (1998).

  34. Chou JJ, Shakhnovich EI: A Study on Local-Global Cooperativity in Protein Collapse. J. Phys. Chem. B, 103, 2535-2542 (1999).

  35. Chou JJ: A Formulation for Correlating Properties of Peptides and Its Application to Predicting Human Immunodeficiency Virus Protease-Cleavable Sites in Proteins. Biopolymers, 33, 1405-1414 (1993).

  36. Chou JJ: Predicting Cleavability of Peptide Sequences by HIV Protease via Correlation-Angle Approach. J. Protein Chem., 12, 291-302 (1993).

  37. Chou JJ, Zhang CT: A Joint Prediction of the Folding Types of 1490 Human Proteins from their Genetic Codons. J. Theor. Biol., 161, 251-262 (1993).

  38. Althaus IW, Chou JJ, Gonzales AJ, Deibel MR, Chou KC, Kezdy FJ, Romero DL, Aristoff PA, Tarpley WG, Reusser F: Steady-state Kinetic Studies with the Non-nucleoside HIV-1 Reverse Transcriptase Inhibitor U-87201E. J Biol Chem., 268, 6119-6124 (1993).

  39. Althaus IW, Chou JJ, Gonzales AJ, Deibel MR, Chou KC, Kezdy FJ, Romero DL, Palmer JR, Thomas RC, Aristoff PA, Tarpley WG, Reusser F: Kinetic Studies with the Non-nucleoside HIV-1 Reverse Transcriptase Inhibitor U-88204E. Biochemistry, 32, 6548-6554 (1993).

  40. Althaus IW, Gonzales AJ, Chou JJ, Romero DL, Deibel MR, Chou KC, Kezdy FJ, Rensnick L, Busso ME, So AG, Downey KM, Thomas RC, Aristoff PA, Tarpley WG, Reusser F: The Quinoline U-78036 is a Potent Inhibitor of HIV-1 Reverse Transcriptase. J. Biol. Chem., 268, 14875-14880 (1993).

©2005 Chou Research Group